Release of tumor necrosis factor (TNF) into mouse peritoneal fluids by OK-432, a streptococcal preparation

An endotoxin-induced serum factor that causes necrosis of tumors.

E A Carswell, Lloyd J. Old, Robert Kassel et al. · Proceedings of the National Academy of Sciences · 1975 · 4.5K citations · Full text

Veterinary Medicine, Immunology, Pathobiology +15

Macrophages as a source of tumoricidal activity (tumor-necrotizing factor)

Daniela N. Männel, Robert N. Moore, Stephan E. Mergenhagen · Infection and Immunity · 1980 · 392 citations · Full text

Life Sciences, Immunology, Microbiology +10

Tumour-necrosis factor from the rabbit. I. Mode of action, specificity and physicochemical properties

N Matthews, J. Watkins · British Journal of Cancer · 1978 · 174 citations

Veterinary Medicine, Immunology, Immunopathology +5

Clinical studies on cell-mediated immunity in patients with malignant disease I. Effect of immunotherapy with OK-432 on lymphocyte subpopulation and phytomitogen responsivenessin vitro

Takashi Hoshino · Cancer · 1980 · 159 citations

Life Sciences, Immunology, Oncology +15

Corynebacterium parvum as the Priming Agent in the Production of Tumor Necrosis Factor in the Mouse2

Saul Green, Areta Dobrjansky, Mary Ann Chiasson et al. · JNCI Journal of the National Cancer Institute · 1977 · 123 citations

Life Sciences, Immunology, Pathobiology +12