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Insertion of expanded CAG trinucleotide repeat motifs into a yeast artificial chromosome containing the human Machado–Joseph disease gene

Yeast Artificial ChromosomeChromosome DynamicsChromatin StructureGenetic DisorderNatural SciencesGeneticsMolecular BiologyYeastMolecular GeneticsDisease Gene IdentificationGenomicsChromosomal RearrangementMedicine