A convenient method for the synthesis of 2-amino substituted aza-heterocycles from N,N′-disubstituted thioureas using TsCl/NaOH

Clonidine binds to imidazole binding sites as well as α2-adrenoceptors in the ventrolateral medulla

Paul Ernsberger, Mary P. Meeley, J. John Mann et al. · European Journal of Pharmacology · 1987 · 445 citations

Medicine, Pharmacology, Physiology +7

Functional properties of the rat Na/H exchanger NHE-2 isoform expressed in Na/H exchanger-deficient Chinese hamster ovary cells.

Frank H. Yu, Gary E. Shull, John Orlowski · Journal of Biological Chemistry · 1993 · 136 citations · Full text

Medicine, Biochemistry, Pharmacology +8

Amidines and related compounds. 6. Structure-activity relations of antihypertensive and antisecretory agents related to clonidine

Timothy Jen, Helene Van Hoeven, William Groves et al. · Journal of Medicinal Chemistry · 1975 · 59 citations

Pharmacy, Medicinal Chemistry, Pharmacology +8

Synthesis of 2-(alkylamino)benzimidazoles

James J. Perkins, Amy E. Zartman · Tetrahedron Letters · 1999 · 57 citations

Structure et réactivité des benzoxazoles: étude par résonance magnétique nucléaire du carbone-13

Jeanine Llinarés, Jean‐Pierre Galy, Robert Faure et al. · Canadian Journal of Chemistry · 1979 · 46 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9