Familial Incidence of Diabetes in Hyperthyroidism

Abstract

Article1 November 1961Familial Incidence of Diabetes in HyperthyroidismLAWRENCE V. PERLMAN, M.D.LAWRENCE V. PERLMAN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-55-5-796 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHyperthyroidism and diabetes mellitus have certain similarities. Not only are the symptoms of the two conditions (fatigue, anxiety, and weight loss) comparable; hyperthyroid patients are more prone than normal individuals to develop diabetes, and diabetics are more apt to become hyperthyroid. Indeed, several observers have postulated that the two disorders, whose etiologies remain obscure, may be peripheral manifestations of a common central metabolic disorder (1, 2). Since diabetes is known to be an inherited disease, albeit a condition that develops late in life, and since there is a strong familial pattern to hyperthyroidism, it seemed reasonable to investigate the inheritance...References1. JOSLINROOTWHITEMARBLE EHPA: The Treatment of Diabetes Mellitus, Lea & Febiger, Philadelphia, 1946, p. 726. Google Scholar2. LABBEPETRESCO MM: Les alterations des glandes endocrenes dans le diabete sucre. Ann. Anat. Path. (Par.) 11: 761, 1934. Google Scholar3. REVENO W: Thiouracil effect in diabetes mellitus complicated by hyperthyroidism. Amer. J. Med. Sci. 211: 174, 1946. CrossrefMedlineGoogle Scholar4. MEANS JH: Thyroid and Its Diseases, 2nd Ed., J. B. Lippincott Co., Philadelphia, 1948, p. 296. Google Scholar5. RUDYBLUMGARTBERLIN AHLDD: A case of diabetes treated by total ablation of the normal thyroid gland. Amer. J. Med. Sci. 190: 51, 1935. CrossrefGoogle Scholar6. LAHEYALLANMURPHY FWR: Hyperthyroidism and diabetes. Trans. Amer. Ass. 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BARTELS E: Heredity in Graves Disease, Einar Munksgaard, Copenhagen, 1941, p. 140. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Washington, D. C.Supported in part by a summer fellowship from the James Hudson Brown Fund of Yale University.Requests for reprints should be addressed to Philip K. Bondy, M.D., Professor of Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven 11, Conn. 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