Synthesis of a novel magnetic drug delivery system composed of doxorubicin-conjugated Fe3O4 nanoparticle cores and a PEG-functionalized porous silica shell

Abstract

Coating a layer of PEG functionalized porous silica shell onto doxorubicin-conjugated Fe(3)O(4) nanoparticles, we demonstrated, provides a number of combined advantages in view of the magnetic carrier's therapeutic functionality to treat tumors.