Perfragilins A and B, Cytotoxic Isoquinolinequinones from the Bryozoan Membranipora perfragilis

Abstract

Detailed spectroscopic and cytotoxicity data are reported for two new isoquinolinequinones, perfragilins A [1] and B [2], which were isolated from the bryozoan Membranipora perfragilis collected in South Australia. Both compounds, which are speculated to be of microbial origin, contain a relatively uncommon thiomethyl ether functionality.