Concepedia

Relaxin decreases renal interstitial fibrosis and slows progression of renal disease

Sandra L. Garber, Yelena Mirochnik, Carolyn Brecklin, Elaine Unemori, Ashok K. Singh, Leonid Slobodskoy, Beverly H. Grove, José A.L. Arruda, George Dunea

Kidney International · 2001 · 151 citations · 12 references

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References

12

Expression of transforming growth factor-β isoforms in human glomerular diseases

Tatsuo Yamamoto, Nancy A. Noble, Arthur H. Cohen et al. · Kidney International · 1996 · 420 citations

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Sustained expression of TGF-β1 underlies development of progressive kidney fibrosis

Tatsuo Yamamoto, Nancy A. Noble, Diane E. Miller et al. · Kidney International · 1994 · 411 citations

, , +15

Relaxin induces an extracellular matrix-degrading phenotype in human lung fibroblasts in vitro and inhibits lung fibrosis in a murine model in vivo.

Elaine Unemori, L Pickford, Adam Salles et al. · Journal of Clinical Investigation · 1996 · 341 citations · Full text

, , +17

Relaxin modulates synthesis and secretion of procollagenase and collagen by human dermal fibroblasts.

Elaine Unemori, Edward P. Amento · Journal of Biological Chemistry · 1990 · 321 citations · Full text

, , +12

Relaxin is a potent renal vasodilator in conscious rats

Lee A. Danielson, O. D. Sherwood, Kirk P. Conrad · Journal of Clinical Investigation · 1999 · 274 citations · Full text

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