Melatonin plasma response to MAO inhibitor: Influence on human pineal activity?

Abstract

Strong negative correlation has been observed between nighttime (physiological) elevation of plasma melatonin and plasma melatonin increase induced by a single dose of MAO inhibitor, tranylcypromine. The possible use of acute plasma melatonin response to MAO inhibitor as a functional test for the evaluation of human pineal activity is discussed.