Prognostic significance of p53 overexpression in gastric and colorectal carcinoma

Mutations in the p53 gene occur in diverse human tumour types

Janice Nigro, Suzanne J. Baker, Antonette C. Preisinger et al. · Nature · 1989 · 2.8K citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas

Suzanne J. Baker, Eric R. Fearon, Janice Nigro et al. · Science · 1989 · 2.1K citations

Life Sciences, Genetics, Oncology +16

The p53 proto-oncogene can act as a suppressor of transformation

Cathy A. Finlay, Philip W. Hinds, Arnold J. Levine · Cell · 1989 · 2K citations

Medicine, Molecular Biology, Oncology +12

p53: A Frequent Target for Genetic Abnormalities in Lung Cancer

Takashi Takahashi, Marion M. Nau, Itsuo Chiba et al. · Science · 1989 · 1.2K citations

Medicine, Genetics, Molecular Genetics +15

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life.

Cathy A. Finlay, Philip W. Hinds, Tse‐Hua Tan et al. · Molecular and Cellular Biology · 1988 · 1.1K citations · Full text

Medicine, Genetics, Molecular Biology +14