MYCN-status in neuroblastoma: characteristics of tumours showing amplification, gain, and non-amplification

Association of Multiple Copies of the N-<i>myc</i>Oncogene with Rapid Progression of Neuroblastomas

Robert C. Seeger, Garrett M. Brodeur, Harland N. Sather et al. · New England Journal of Medicine · 1985 · 2K citations

Medicine, Molecular Genetics, Oncology +17

Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour

Manfred Schwab, Kari Alitalo, Karl-Heinz Klempnauer et al. · Nature · 1983 · 1.4K citations

Medicine, Genetics, Oncology +14

Conditional expression of N-myc in human neuroblastoma cells increases expression of alpha-prothymosin and ornithine decarboxylase and accelerates progression into S-phase early after mitogenic stimulation of quiescent cells.

W. Lutz, M. Stöhr, Jürgen Schürmann et al. · PubMed · 1996 · 316 citations

Life Sciences, Cell Biology, Molecular Biology +16

Allelic deletion at 11q23 is common in MYCN single copy neuroblastomas

Chun Guo, Peter S. White, Matthew J. Weiss et al. · Oncogene · 1999 · 249 citations

Medicine, Genetics, Molecular Genetics +8

Biologic Factors Determine Prognosis in Infants With Stage IV Neuroblastoma: A Prospective Children’s Cancer Group Study

Mary Lou Schmidt, John N. Lukens, Robert C. Seeger et al. · Journal of Clinical Oncology · 2000 · 240 citations

Medicine, Oncology, Pediatrics +13