OSTEOPETROSIS (MARBLE BONES)<subtitle>Report of a Case with Special Reference to Early Roentgenologic and Pathological Findings</subtitle>

Abstract

OSTEOPETROSIS (Albers-Schönberg¹disease) is a rare condition in which the normal bony structure becomes thickened and sclerotic because of an increase in the number and size of the trabeculae and excessive calcareous deposit. McCune and Bradley²in a critical review of the literature up to 1934 found 69 cases which could be considered as due to this disease. By 1941 Higinbotham and Alexander³were able to collect 135 cases including their own, and by 1947 Pines and Lederer⁴had increased the number of reported cases to 148. In the past three years we were able to find 26 additional reported cases, making the number 174 up to 1950. The confusion of this disease, especially in the earlier days, with various other bone conditions, notably certain cases of osteopoikilosis, melorheostosis and osteosclerosis from fluorine or phosphorus poisoning or myelosclerosis, makes it difficult in some cases to render