Neuropediatrics · 1992 · 25 citations · 0 references
NeuropsychologyBrain FunctionBrain DevelopmentDevelopmental Cognitive NeuroscienceNeurodevelopmentBrain LesionSocial SciencesBrain MaturationNeurologyBrain StructureT2 ValuesNeuroimagingBrain ImagingNeurological AssessmentMaturational ChangesNeuroimaging BiomarkersNeuroanatomyPediatricsT2 Values DecreaseNeuroscienceMedicine
MRI is a noninvasive method to assess the maturation of the brain. T2 values decrease after birth in proportion to histologically ascertained maturational changes of cortical and subcortical structures. T2 values of 8 anatomical brain structures were sampled in 5 healthy children aged 8 years, four healthy children aged 10 years and 8 healthy adults aged 24 or 25 years. The results of the study indicated that T2 values decrease after the first decade of life, consistent with maturational changes of the CNS persisting into the 2nd and 3rd decades of life.