Associations of GAD65- and IA-2-Autoantibodies With Genetic Risk Markers in New-Onset IDDM Patients and Their Siblings. The Belgian Diabetes Registry - Concepedia

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Associations of GAD65- and IA-2-Autoantibodies With Genetic Risk Markers in New-Onset IDDM Patients and Their Siblings. The Belgian Diabetes Registry

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References

1997

Year

Christina Vandewalle, Alberto Falorni, Åke Lernmark, Patrick Goubert, Harry Dorchy, Willy Coucke, Crispin Semakula, Bart Van Der Auwera, Léon Kaufman, Frans Schuit,

Abstract

Both GAD65- and IA-2-Abs exhibit higher prevalences in presence of HLA-DQ- and/or INS-genetic risk markers. Their respective associations differ with age at clinical onset, suggesting a possible usefulness in the identification of subgroups in this heterogeneous disease.