Exercise Training Attenuates Postoperative Pain and Expression of Cytokines and N-methyl-D-aspartate Receptor Subunit 1 in Rats

Abstract

These results suggest that exercise training decreases persistent postsurgical pain caused by SMIR surgery. There appears to be a protective effect, probably relating to the decrease of NR1, TNF-α, and IL-6 expression in the spinal cord of SMIR rats, after exercise intervention.