Investigation of the Pharmacokinetics of Romiplostim in Rodents with a Focus on the Clearance Mechanism

General Pharmacokinetic Model for Drugs Exhibiting Target-Mediated Drug Disposition

Donald E. Mager, William J. Jusko · Journal of Pharmacokinetics and Pharmacodynamics · 2001 · 587 citations

Pharmacy, Pharmacokinetics, Pharmacology +14

The reciprocal relationship of thrombopoietin (c-Mpl ligand) to changes in the platelet mass during busulfan-induced thrombocytopenia in the rabbit

DJ Kuter, RD Rosenberg · Blood · 1995 · 395 citations · Full text

Medicine, Hematology, Immunology +12

Pharmacodynamics and pharmacokinetics of AMG 531, a novel thrombopoietin receptor ligand

Bo Wang, JL Nichol, John T. Sullivan · Clinical Pharmacology & Therapeutics · 2004 · 294 citations

Medicine, Pharmacokinetics, Pharmacology +13

Interaction of thrombopoietin with the platelet c‐mpl receptor in plasma: binding, internalization, stability and pharmacokinetics

Junzhi Li, Yuping Xia, David J. Kuter · British Journal of Haematology · 1999 · 166 citations

Medicine, Hematology, Pharmacology +11

The influence of polymer topology on pharmacokinetics: Differences between cyclic and linear PEGylated poly(acrylic acid) comb polymers

Bo Chen, Katherine Jerger, Jean M. J. Fréchet et al. · Journal of Controlled Release · 2009 · 160 citations · Full text

Pharmacy, Clinical Pharmacokinetics, Pharmacokinetics +14