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Rasmussenʼs encephalitis
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1996
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Autoimmune DiseaseImportant AutoantigenNeurological DisorderMedicineImmunologyAutoimmunityBrain-immune InteractionImmunologic DiseaseNeurologyNeuroscienceEncephalitisExperimental AnimalsNeuropathologyNeuroimmunologyGlutamate Receptor Subunit
Rasmussen's encephalitis is a rare progressive pediatric epileptic syndrome. Recent evidence from experimental animals and patients with the disease suggests an important role for both humoral- and cell-mediated immune mechanisms in the pathogenesis of this disease. The glutamate receptor subunit, GluR3, may be an important autoantigen in the disease.