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Development and validation of a liquid chromatography–tandem mass spectrometry method for simultaneous determination of amlodipine, atorvastatin and its metabolites ortho-hydroxy atorvastatin and para-hydroxy atorvastatin in human plasma and its application in a bioequivalence study

Metabolites Ortho-hydroxy AtorvastatinMedicinePhysiologyBioanalysisMass SpectrometryHuman PlasmaAnalytical ChemistryPharmacotherapyDrug MonitoringLiquid ChromatographyClinical ChemistryMetabolomicsPara-hydroxy AtorvastatinPharmacologyChromatographic AnalysisPharmacokineticsChromatographyDrug Analysis