Antagonism by antidepressants of serotonin S1 and S2 receptors of normal human brain in vitro

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

Peter J. Munson, David Rodbard · Analytical Biochemistry · 1980 · 8.5K citations

Life Sciences, Chemistry, Biomolecular Modeling +11

[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.

J E Leysen, C. J. E. Niemegeers, Jan M. Van Nueten et al. · Molecular Pharmacology · 1982 · 1.1K citations

Medicine, Medicinal Chemistry, Pharmacology +17

Long-Term Antidepressant Treatment Decreases Spiroperidol-Labeled Serotonin Receptor Binding

Stephen J. Peroutka, Solomon H. Snyder · Science · 1980 · 838 citations

Medicine, Pharmacology, Psychiatry +17

Blockade by antidepressants and related compounds of biogenic amine uptake into rat brain synaptosomes: Most antidepressants selectively block norepinephrine uptake

Elliott Richelson, Michael Pfenning · European Journal of Pharmacology · 1984 · 530 citations

Medicine, Neuroscience, Pharmacology +17

Antagonism by antidepressants of neurotransmitter receptors of normal human brain in vitro.

Elliott Richelson, Albert N. Nelson · Journal of Pharmacology and Experimental Therapeutics · 1984 · 342 citations

Medicine, Neuroscience, Pharmacology +17