Immunostaining of the p30/32MIC2 antigen and molecular detection of EWS rearrangements for the diagnosis of Ewing's sarcoma and peripheral neuroectodermal tumor

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

S M Hsu, Laurence Raine, Herbert Fanger · Journal of Histochemistry & Cytochemistry · 1981 · 14.3K citations · Full text

Life Sciences, Immunology, Immunopathology +8

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

Olivier Delattre, Jessica Zucman‐Rossi, Béatrice Plougastel-Douglas et al. · Nature · 1992 · 1.9K citations

Life Sciences, Genetics, Molecular Genetics +17

The Ewing Family of Tumors -- A Subgroup of Small-Round-Cell Tumors Defined by Specific Chimeric Transcripts

Olivier Delattre, Jessica Zucman‐Rossi, Thomas Melot et al. · New England Journal of Medicine · 1994 · 1.1K citations · Full text

Medicine, Oncology, Pathology +15

A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS–family transcription factor, ERG

Poul H. Sorensen, Stephen L. Lessnick, Dolores López‐Terrada et al. · Nature Genetics · 1994 · 745 citations

Medicine, Genetics, Molecular Genetics +12

MIC2 is a specific marker for ewing's sarcoma and peripheral primitive neuroectodermal tumors. Evidence for a common histogenesis of ewing's sarcoma and peripheral primitive neuroectodermal tumors from MIC2 expression and specific chromosome aberration

Inge M. Ambros, Peter F. Ambros, Sabine Strehl et al. · Cancer · 1991 · 657 citations · Full text

Life Sciences, Genetics, Oncology +17