Role of Hemochromatosis C282Y and H63D Mutations in <i>HFE</i> Gene in Development of Type 2 Diabetes and Diabetic Nephropathy

Abstract

In conclusion, our study is the first to indicate that being a carrier of the H63D hemochromatosis mutation is a risk factor for nephropathy in type 2 diabetic patients. We also confirmed previous observations that the frequency of the 282Y mutation was higher in patients with type 2 diabetes than it was in the general population of healthy subjects.