Novel Silane Coupling Agents Containing a Photolabile 2-Nitrobenzyl Ester for Introduction of a Carboxy Group on the Surface of Silica Gel

Abstract

Abstract Silane coupling agents containing a carboxy group are not known because the chloro- or alkoxy group is reactive to the carboxylic acid. In this study, silane coupling agents bearing a 2-nitrobenzyl ester as a protecting group of carboxylic acid were synthesized and applied for surface modification of silica gel followed by uv irradiation under neutral conditions to generate carboxy groups on the surface.