Hoxb5b Acts Downstream of Retinoic Acid Signaling in the Forelimb Field to Restrict Heart Field Potential in Zebrafish

Mutations in human cause limb and cardiac malformation in Holt-Oram syndrome

Craig T. Basson, David R. Bachinsky, Robert C. Lin et al. · Nature Genetics · 1997 · 1.1K citations

Medicine, Genetics, Molecular Genetics +16

Embryonic retinoic acid synthesis is essential for early mouse post-implantation development

Karen Niederreither, Vemparala Subbarayan, Pascal Dollé et al. · Nature Genetics · 1999 · 1.1K citations

Life Sciences, Developmental Biology, Developmental Signaling +13

p53 Activation by Knockdown Technologies

Mara E. Robu, Jon D. Larson, Aidas Nasevicius et al. · PLoS Genetics · 2007 · 1K citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family

Newbury-Ecob Ra, David I. Wilson, Andrew R.J. Curtis et al. · Nature Genetics · 1997 · 929 citations

Life Sciences, Genetics, Molecular Genetics +8

Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5

Osamu Chisaka, Mario R. Capecchi · Nature · 1991 · 853 citations

Life Sciences, Developmental Biology, Genetics +14