DIFLUOROMETHYLORNITHINE FOR ARSENO-RESISTANT TRYPANOSOMA BRUCEI GAMBIENSE SLEEPING SICKNESS

Polyamine Metabolism: A Potential Therapeutic Target in Trypanosomes

Carol Bacchi, Henry C. Nathan, S. H. Hutner et al. · Science · 1980 · 391 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Treatment of gambiense sleeping sickness in the Sudan with oral DFMO (DL-α-difluoromethylornithine), an inhibitor of ornithine decarboxylase; first field trial

Simon Van Nieuwenhove, Paul J. Schechter, J. Declercq et al. · Transactions of the Royal Society of Tropical Medicine and Hygiene · 1985 · 152 citations

Medicine, Pharmacology, Pharmacotherapy +6

African Trypanosomiasis.

Annals of Internal Medicine · 1970 · 131 citations

Kinetics of α-difluoromethylornithine: An irreversible inhibitor of ornithine decarboxylase

Klaus D. Haegele, R. G. Alken, Jeffrey Grove et al. · Clinical Pharmacology & Therapeutics · 1981 · 77 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Clinical and Pathological Aspects of Human African Trypanosomiasis (T. B. Gambiense) with Particular Reference to Reactive Arsenical Encephalopathy

L Haller, Hume Adams, F Mérouze et al. · American Journal of Tropical Medicine and Hygiene · 1986 · 74 citations

Medicine, Neurology, Pathology +15