Lack of Evidence of Acute Ischemic Tissue Change in Transient Global Amnesia on Single-Shot Echo-Planar Diffusion-Weighted MRI

Abstract

We were unable to detect ADC or acute T2 changes with echo-planar DW MRI in patients with TGA, which suggests that mechanisms other than ischemic infarction may cause TGA. We did not identify spreading depression-associated changes of the ADC. Further refinement of MRI sequences may be necessary to detect subtle or transient signal change in brain parenchyma.