ANTIBIOTIC 6640, A NEW MICROMONOSPORA-PRODUCBD AMINOGLYCOSIDE ANTIBIOTIC

Abstract

Antibiotic 6640 is a new aminoglycoside antibiotic isolated from fermentation broths of a new species of the genus Micromonospora, named Micromonospora inyoensis. It has been differentiated from other known related antibiotics by a variety of chemical and biological methods. Its spectrum of activity appears to be quite similar to that of gentamicin in vitro and in vivo. The acute toxicity is approximately twice that of gentamicin in mice.