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Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D1, D2 and serotonin 5-HT1A multi-action profile

Medicinal ChemistryPsychoactive DrugFunctional SelectivityMedicinePsychotropic MedicationPsychopharmacologyTetrahydroprotoberberine DerivativesNew Antipsychotic AgentsNeuroscienceDopamine D1DopaminePharmacologySocial SciencesDrug Discovery