DIDS Reduces Ischemia/Reperfusion-Induced Myocardial Injury in Rats

Abstract

Taken together, our data revealed that DIDS may protect cardiomyocytes against I/R injury as evidenced by improved cardiac function, Bcl-2, Akt phosphorylation, and reduced myocardial apoptosis, Bax expression, ROS production and myocardial infarct size.