Concepedia

The ROS Production Induced by a Reverse-Electron Flux at Respiratory-Chain Complex 1 is Hampered by Metformin

Cécile Batandier, Bruno Guigas, Dominique Détaille, Mohamad Yehia A. El-Mir, Éric Fontaine, Michel Rigoulet, Xavier Leverve

Journal of Bioenergetics and Biomembranes · 2006 · 303 citations · 35 references

DOI

Concepts

References

35

Biochemistry and molecular cell biology of diabetic complications

Michael Brownlee · Nature · 2001 · 9K citations

, , +14

Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)

The Lancet · 1998 · 8.3K citations

, , +17

Oxyl radicals, redox-sensitive signalling cascades and antioxidants

Cellular Signalling · 2007 · 4.8K citations

, , +14

Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group.

PubMed · 1998 · 4.3K citations

, , +17

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

Takeshi Nishikawa, Diane Edelstein, Xue Du et al. · Nature · 2000 · 4.3K citations

, , +14