Optimum Force and Duration of Toothbrushing to Enhance Gingival Fibroblast Proliferation and Procollagen Type I Synthesis in Dogs

Abstract

Toothbrushing at certain forces and durations enhanced the proliferative activity and procollagen synthesis of gingival fibroblasts. The toothbrushing duration that increased procollagen synthesis (10 seconds) was shorter than that which increased fibroblast proliferative activity (20 seconds).