PGH2, TxA2 and PGI2 have potent and differentiated actions on human uterine contractility

Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac arteries and inhibits platelet aggregation

Stuart Bunting, Salvador Moncada, John R. Vane et al. · Prostaglandins · 1976 · 955 citations

Medicine, Physiology, Signal Transduction +11

HUMAN ARTERIAL AND VENOUS TISSUES GENERATE PROSTACYCLIN (PROSTAGLANDIN X), A POTENT INHIBITOR OF PLATELET AGGREGATION

Salvador Moncada, E.A. Higgs, John R. Vane · The Lancet · 1977 · 887 citations

Medicine, Hematology, Pharmacology +13

Prostacyclin (PGX) is the endogeneous metabolite responsible for relaxation of coronary arteries induced by arachidonic acid

Gregory J. Dusting, Salvador Moncada, John R. Vane · Prostaglandins · 1977 · 412 citations

Medicine, Cardiology, Pharmacology +14

STUDIES ON 5‐HYDROXYTRYPTAMINE STORES IN PINEAL GLAND OF RAT

Åke Bertler, B. Falck, Christer Owman · Acta Physiologica Scandinavica · 1964 · 394 citations

Life Sciences, Neurobiology, Physiology +11

Resolution of prostaglandin endoperoxide synthase and thromboxane synthase of human platelets.

Sven Hammarström, Pierre Falardeau · Proceedings of the National Academy of Sciences · 1977 · 191 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17