VASCULARIZATION OF SECOND-SET HOMOGRAFTS IN THE RAT, WITH PARTICULAR REFERENCE TO THE WHITE GRAFT

Abstract

A histochemical study of diphosphopyridine nucleotide diaphorase activity in second-set skin homografts in rats during the first 3 days after transplantation demonstrated: 1. an ingrowth of new host capillaries into the deep layer of the dermis of both typical second-set grafts and white grafts during the first 24 hours after grafting; 2. the cessation of vascular ingrowth in white grafts between 24 and 48 hr; 3. an atypical homograft reaction of second-set grafts transplanted 5 days after first-set grafting; and 4. the variability of type of homograft reaction occurring in second-set grafts transplanted 6 and 7 days after-set grafting.