Potentiation of irinotecan sensitivity by Se-methylselenocysteine in an in vivo tumor model is associated with downregulation of cyclooxygenase-2, inducible nitric oxide synthase, and hypoxia-inducible factor 1α expression, resulting in reduced angiogenesis

Publication | Closed Access

DOI

Citations

References

2006

Year

M-B Yin, Z-R Li, Károly Tóth, Shousong Cao, Farukh A. Durrani, Gunnar Hapke, A. Bhattacharya, Rami G. Azrak, C Frank, Youcef M. Rustum

Oncogene

Redox SignalingTumor BiologyAngiogenesisIrinotecan SensitivityRedox RegulatorMedicineVivo Tumor ModelHypoxia-inducible Factor 1αCancer Cell BiologyVascular BiologyReactive Oxygen SpeciePharmacologyCell BiologyRedox BiologyCancer ResearchOxidative Stress