Increasing levels of wild-type CREB up-regulates several activity-regulated inhibitor of death (AID) genes and promotes neuronal survival

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

Gustavo González, Marc Montminy · Cell · 1989 · 2.5K citations

Somatostatin Gene Transcription, Molecular Regulation, Cellular Physiology +17

Cell Survival Promoted by the Ras-MAPK Signaling Pathway by Transcription-Dependent and -Independent Mechanisms

Azad Bonni, Anne Brunet, Anne E. West et al. · Science · 1999 · 1.9K citations

Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways

Giles E. Hardingham, Yuko Fukunaga, Hilmar Bading · Nature Neuroscience · 2002 · 1.7K citations

Synaptic Plasticity, Molecular Physiology, Neurophysiology +11

Regulation of Gene Expression in Hippocampal Neurons by Distinct Calcium Signaling Pathways

Hilmar Bading, David D. Ginty, Michael E. Greenberg · Science · 1993 · 1.2K citations

Disruption of CREB function in brain leads to neurodegeneration

Theo Mantamadiotis, Thomas Lemberger, Susanne C. Bleckmann et al. · Nature Genetics · 2002 · 688 citations · Full text

Neurodegenerative Diseases, Creb Function, Neurological Function +6