Supernatant of Aged Erythrocytes Causes Lung Inflammation and Coagulopathy in a “Two-Hit”In Vivo Syngeneic Transfusion Model

Abstract

The 2 cases illustrate that TRALI can occur both in the absence and in the presence of another ALI risk factor. Awareness should be increased that all patients exhibiting ALI within 6 hours of a blood transfusion, including possible TRALI, should be reported to the blood bank.