Pediatrics International · 2006 · 28 citations · 7 references
MedicineChild HealthPediatricsPediatric PulmonologyPulmonary Function TestingPulmonologyDry Powder InhalersInhalation TherapyMetered-dose InhalersPeak Expiratory FlowPediatric Pulmonary Function TestingRespiratory MonitoringInhaler ResistanceInspiratory Flow LimitationInspiratory Flow ResistanceInspiratory Resistance TestingInternal ResistanceMetered-dose Inhaler UsePressurized Metered Dose InhalersRespiratory Assessment In Children
BACKGROUND: Although current guidelines recommend the pressurized metered-dose inhaler with a spacer for preschool children with asthma, dry powder inhalers (DPI) may be a valuable treatment alternative. METHODS: To evaluate the ability of preschool children to inhale through DPI, peak inspiratory flow rates (PIFR) of 57 healthy children aged 3-6 years were measured with In-Check Meter after practising with an instructor. Two different calibrated resistances were attached to the Meter to mimic the internal resistance of each inhaler; Diskus and Turbuhaler. RESULTS: The ability of children to generate adequate inspiratory flow increased with age. The percentages of the 3-, 4-, 5-, and 6-year-old children who were able to inhale reliably through the devices were 30% (3/10), 79.0% (15/19), 100% (16/16), and 100% (12/12), respectively. In these children, 100%, 93.3%, 100%, and 100% achieved an adequate PIFR for the Diskus (30 L/min). In contrast, 66.7%, 66.7%, 62.5%, and 91.7% generated an adequate PIFR for the Turbuhaler (60 L/min). CONCLUSIONS: The In-Check Meter is a useful device to assess the ability of preschool children to generate adequate PIFR for each inhaler. Most children aged > or =5 years could use DPI.
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Peak inspiratory flow through Turbuhaler in acute asthma
PH Brown, AC Ning, A P Greening et al. · European Respiratory Journal · 1995 · 81 citations · Full text