Concepedia

Anti-Neuropilin-1 (MNRP1685A): Unexpected Pharmacokinetic Differences Across Species, from Preclinical Models to Humans

Shuang Bai, Lisa A. Damico‐Beyer, Denise Jin, Wei‐Ching Liang, Yan Wu, Frank‐Peter Theil, Amita Joshi, Yanmei Lu, John Lowe, Mauricio Maia,

Pharmaceutical Research · 2012 · 38 citations · 29 references

DOI

Concepts

References

29

Neuropilin-1 Is Expressed by Endothelial and Tumor Cells as an Isoform-Specific Receptor for Vascular Endothelial Growth Factor

Shay Söker, Seiji Takashima, Hua Miao et al. · Cell · 1998 · 2.5K citations · Full text

, , +15

Neuropilin Is a Receptor for the Axonal Chemorepellent Semaphorin III

Zhigang He, Marc Tessier‐Lavigne · Cell · 1997 · 1.1K citations · Full text

, , +8

A requirement for neuropilin-1 in embryonic vessel formation

Takahiko Kawasaki, Takashi Kitsukawa, Yoko Bekku et al. · Development · 1999 · 820 citations

, , +13

Blocking Neuropilin-1 Function Has an Additive Effect with Anti-VEGF to Inhibit Tumor Growth

Qi Pan, Yvan H. Chanthery, Wei‐Ching Liang et al. · Cancer Cell · 2007 · 531 citations · Full text

, , +14

Animal scale-up

Robert L. Dedrick · Journal of Pharmacokinetics and Biopharmaceutics · 1973 · 394 citations