Seizure‐like discharges induced by 4‐aminopyridine in the olfactory system of the in vitro isolated guinea pig brain

Abstract

Our data show that olfactory neuronal networks sustain the generation of seizure-like activities that are independent from those observed in adjacent and connected limbic cortex regions. The data support the concept that functionally and anatomically hard-wired networks generate region-specific seizure patterns that could be substrates for system epilepsy.