The Significance of Candidemia

Abstract

Article1 September 1967The Significance of CandidemiaCHARLES A. ELLIS, M.D., MARTIN L. SPIVACK, M.D., PH.D.CHARLES A. ELLIS, M.D.Search for more papers by this author, MARTIN L. SPIVACK, M.D., PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-67-3-511 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMembers of the genusCandidaare common saprophytes on the mucous membranes and in the gastrointestinal tract of man (1, 2). The ability of these microorganisms to emerge as clinically significant pathogens has been the subject of recent attention (3-5). Although there is general agreement that the increasing prevalence ofCandidaspecies as opportunistic invaders began with the use of modern chemotherapy, the precise determinants of the altered pathogenicity ofCandidain the human host are not clear. Such diverse factors as antibiotic therapy (6, 7), adrenocortical steroids (8), prolonged intravenous therapy, particularly using indwelling venous catheters (9, 10), glucose...References1. ROSEBURY T: Microorganisms Indigenous to Man. McGraw-Hill Book Co., Inc., New York, 1962, p. 230. Google Scholar2. WINNERHURLEY HIR: Candida Albicans. J. & A. Churchill, Ltd., London, 1964. Google Scholar3. BRAUDEROCK AIJA: The syndrome of acute disseminated moniliasis in adults. Arch. Intern. Med. (Chicago) 104: 91, 1959. CrossrefGoogle Scholar4. LOURIASTIFFBENNETT DBDPB: Disseminated moniliasis in the adult. Medicine (Balt.) 41: 307, 1962. CrossrefGoogle Scholar5. DENNISMILLERPETERSON DMJCG: Candida septicemia. Surg. Gynec. Obstet. 119: 520, 1964. MedlineGoogle Scholar6. KEYEMAGEE JDWE: Fungal diseases in a general hospital: a study of 88 patients. Amer. J. Clin. Path. 26: 1235, 1956. CrossrefMedlineGoogle Scholar7. SEELIG MS: The role of antibiotics in the pathogenesis of Candida infections. 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Annual review of significant publications.ERYTHROPOIETIC PROTOPORPHYRIA IN TWO SISTERS 1 September 1967Volume 67, Issue 3_Part_1 Page: 511-522 Keywords Candida Chemotherapy Gastrointestinal tract Glucose Infectious diseases Mucous membranes Opportunistic pathogens Pathogens Pulmonary diseases Steroids ePublished: 1 December 2008 Issue Published: 1 September 1967 PDF downloadLoading ...