Evidence for the direct interaction of reduced metronidazole derivatives with DNA bases

Theory of Stationary Electrode Polarography. Single Scan and Cyclic Methods Applied to Reversible, Irreversible, and Kinetic Systems.

Richard S. Nicholson, Irving. Shain · Analytical Chemistry · 1964 · 5.1K citations

Natural Sciences, Chemistry, Analytical Chemistry +14

Reduction of nitroimidazoles in vitro and DNA damage

David Edwards · Biochemical Pharmacology · 1986 · 143 citations

Pharmacy, Molecular Biology, Pharmacology +10

Electrochemical Characteristics of Nitro-Heterocyclic Compounds of Biological Interest: I. The Influence of Solvent

Joanne H. Tocher, David I. Edwards · Free Radical Research Communications · 1988 · 54 citations

Natural Sciences, Chemistry, Medicinal Chemistry +13

Modification of guanine derivatives by reduced 2-nitroimidazoles.

A. J. Varghese, G. F. Whitmore · PubMed · 1983 · 52 citations

Pharmacy, Biochemistry, Chemistry +8

In vitro reductive activation of nitroimidazoles

Paul Declerck, C. J. De Ranter · Biochemical Pharmacology · 1986 · 48 citations

Medicine, Medicinal Chemistry, Pharmacology +3