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Metformin-induced stimulation of AMP-activated protein kinase in β-cells impairs their glucose responsiveness and can lead to apoptosis

Molecular PhysiologySignal TransductionGlucose ResponsivenessAmp-activated Protein KinaseMedicineDiabetesApoptosisPhysiologyCell DeathMetformin-induced StimulationMetabolic RegulationCellular BiochemistryPharmacologyCell BiologyCell SignalingCellular PhysiologyInsulin Signaling