Lipid hydroperoxide and markers of renal disease susceptibility in African‐Caribbean and Caucasian patients with Type 2 diabetes mellitus

Abstract

In this group of Type 2 diabetic patients an increase in LOOH is associated with abnormal urinary albumin excretion. African-Caribbean origin was a determinant of LOOH independently of microalbuminuria. It is postulated that increased oxidative stress is of pathophysiological significance in accelerating the development of renal disease in African-Caribbean patients.