One‐Pot Synthesis of Triazolothiadiazepine 1,1‐Dioxide Derivatives <i>via</i> Copper‐Catalyzed Tandem [3+2] Cycloaddition/<i>N</i>‐Arylation

Abstract

Abstract A practical and efficient synthesis of triazolothiadiazepine‐1,1‐dioxide derivatives via copper‐catalyzed [3+2] cycloaddition, followed by N ‐arylation is described. The method is also applicable to the synthesis of indoline‐ and thiophene‐fused triazolothiadiazepine 1,1‐dioxide derivatives.