Luteal oxytocin and monoestry in the roe deer <i>Capreolus capreolus</i>

Abstract

The relationship between the corpus luteum and the uterus in terms of the secretion of oxytocin and PGF2 alpha was investigated in free-living and captive roe deer Capreolus capreolus. During the breeding season the corpus luteum contained oxytocin and oxytocin-neurophysin mRNA, and secreted oxytocin in response to administration of the PGF2 alpha analogue cloprostenol. The oxytocin receptor was present in the uterus during the bleeding season and during delayed implantation; however, in contrast to the situation observed in other ruminants in which it has been studied, administered oxytocin did not stimulate uterine secretion of PGF2 alpha. Trophoblast interferon was undetectable at any stage of conceptus development. The absence of the mechanism underlying episodic uterine secretion of PGF2 alpha during luteolysis, which may account for the monoestry of roe deer, is consistent with the previously observed luteolytic effect of the PGF2 alpha analogue.