NGF released from a polymer matrix prevents loss of ChAT expression in basal forebrain neurons following a fimbria-fornix lesion

Polymers for the sustained release of proteins and other macromolecules

Róbert Langer, Judah Folkman · Nature · 1976 · 1.2K citations

Pharmacy, Materials Science, Pharmaceutics +14

Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection.

Lawrence R. Williams, S Varon, Gregory M. Peterson et al. · Proceedings of the National Academy of Sciences · 1986 · 1.1K citations

Life Sciences, Neurobiology, Neuroscience +17

Grafting Genetically Modified Cells to the Damaged Brain: Restorative Effects of NGF Expression

Michael B. Rosenberg, Theodore Friedmann, Robin Robertson et al. · Science · 1988 · 510 citations

Medicine, Neurobiology, Neuroscience +17

Chronic intraventricular injections of nerve growth factor elevate hippocampal choline acetyltransferase activity in adult rats with partial septo-hippocampal lesions

Franz Hefti, A.R. Dravid, Jukka Hartikka · Brain Research · 1984 · 447 citations

Life Sciences, Neurobiology, Neuroscience +13

Production of specific antisera and monoclonal antibodies to choline acetyltransferase: characterization and use for identification of cholinergic neurons.

F. Eckenstein, H. Thoenen · The EMBO Journal · 1982 · 442 citations · Full text

Life Sciences, Neurobiology, Neuroscience +13