Experience of prophylactic thyroidectomy in multiple endocrine neoplasia type 2A kindreds with <i>RET</i> codon 804 mutations

Abstract

We suggest that prophylactic thyroidectomy should not be delayed until adulthood in MEN 2A families carrying codon 804 RET mutations, but should be performed when there is CCH, before the development of MTC, as close as possible to age 6 years, which is the age of the youngest reported case of MTC in '804' families.