Increased Serum IL-10 and Endothelin Levels in Hemolytic Uremic Syndrome Caused by <i>Escherichia coli</i> O157

Abstract

Increased serum endothelin synthesis by Shiga toxin in vivo was proven in HUS secondary to E. coli O157:H7 infection. Increased serum endothelin and IL-10 levels were speculated to be associated with the development of HUS through vascular endothelial damage caused by E. coli O157:H7 infection.