Lipid‐Coated Nanocrystals as Multifunctionalized Luminescent Scaffolds for Supramolecular Biological Assemblies

Abstract

Nanometer light source: Interaction between high-affinity binding sites on lipid-coated nanocrystals (NCs) and different proteins enables the controlled formation of supramolecular nanostructures on micropatterned surfaces (see picture; FRET=fluorescence resonant energy transfer, NTA=nitrilotriacetic acid, His6=hexahistidine). The NCs serve as local light sources emitting light over distances from 1 to more than 10 nm.