Similarly Derived and Cultured HEsc Lines Show Variation in their Developmental Potential Towards Neuronal Cells in Long-Term Culture

Abstract

Simple neurosphere culture is a suitable method for producing hESC-derived neuronal cells that can form functional neuronal networks from a number of hESC lines. The variation in the differentiation potential of hESC lines into neuronal cells must be carefully considered by those comparing various differentiation methods and designing transplantation therapies for neuronal disorders.