Concepedia

The anti-cancer peptide, PNC-27, induces tumor cell lysis as the intact peptide

Kelley A. Sookraj, Wilbur B. Bowne, Victor Adler, Ehsan Sarafraz-Yazdi, Josef Michl, Matthew R. Pincus

Cancer Chemotherapy and Pharmacology · 2010 · 22 citations · 7 references

DOI

Concepts

References

7

Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms

Chafké Ahmed Belmokhtar, Josette Hillion, E. Segal · Oncogene · 2001 · 480 citations

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Peptides from the amino terminal mdm-2-binding domain of p53, designed from conformational analysis, are selectively cytotoxic to transformed cells

Mecheal Kanovsky, Anthony J. Raffo, Lisa Drew et al. · Proceedings of the National Academy of Sciences · 2001 · 89 citations · Full text

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Preferential induction of necrosis in human breast cancer cells by a p53 peptide derived from the MDM2 binding site

N Tamara, Ramon Rosal, Lisa Drew et al. · Oncogene · 2003 · 68 citations

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NMR Solution Structure of a Peptide from the mdm-2 Binding Domain of the p53 Protein that Is Selectively Cytotoxic to Cancer Cells<sup>,</sup>

Ramon Rosal, Matthew R. Pincus, Paul W. Brandt‐Rauf et al. · Biochemistry · 2004 · 39 citations

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PNC‐28, a p53‐derived peptide that is cytotoxic to cancer cells, blocks pancreatic cancer cell growth <i>in vivo</i>

Josef Michl, Bruce Scharf, Anna Laura Schmidt et al. · International Journal of Cancer · 2006 · 30 citations

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