The use of Nasal Epithelial Stem/progenitor Cells to Produce Functioning Ciliated Cells <i>in vitro</i>

Abstract

Our results showed the feasibility of expanding hNESPCs for clinical purpose by using human feeder layer, avoiding components of animal source, while preserving their self-renewal and differentiation potential. This study represents an early step toward a better understanding of hNESPCs, and serum -free media plus human feeder potentially would be an ideal method for making clinical grade hNESPCs on a large scale.